Every ingredient, ranked by its research.
Best proof first. A = strong proof · B = some proof · C = early proof. Tap any ingredient to see its products.
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Every product, side by side
Show all products — compare & sort
All the products in one list. Compare by price per 100 ml to see what’s really cheapest, filter or sort by ingredient to see one ingredient’s products together — then tap Buy.
How the grade works
Each ingredient gets a score out of 10 from its published clinical studies — not brand claims. A = 8–10, B = 4–7, C = 0–3.
The five criteria & the grade definitions
| Criterion | What earns the points | Points |
|---|---|---|
| Human clinical trials | Randomized controlled trials or meta-analyses in people, measuring the claimed effect | 0–2 |
| Guideline or regulatory recognition | Named in clinical guidelines (e.g. American Academy of Dermatology) or approved as a drug for the condition | 0–2 |
| Independent replication | Positive results repeated by research groups with no stake in selling the ingredient | 0–2 |
| Evidence at cosmetic use | Trials tested a topical cosmetic at realistic strengths — not only injections, prescription doses, or in-office peels | 0–2 |
| Safety record | Long, well-documented tolerability at cosmetic strengths, with known and manageable side effects | 0–2 |
Strong · 8–10 points. Multiple trials or meta-analyses, often guideline-backed. The closest thing skincare has to a sure bet.
Moderate · 4–7 points. Real human evidence, with gaps — smaller studies, narrower claims, or formulation caveats. Plausible and partly proven.
Early · 0–3 points. Mostly lab, animal, or injection studies. Popular in marketing well before the cosmetic evidence exists.
Keeping it honest
Studies test ingredients, not products — a high grade means the ingredient is proven, not that every product with it works.
Prices checked November 9, 2026 — the store page always wins. And this guide is educational, not medical advice: stubborn skin problems deserve a dermatologist.
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